All the parishes fall under the Pastoral Commission. The Diocese of Karonga is divided into seven parishes which are grouped into two deaneries, namely: Chitipa and Karonga Deaneries. Chitipa Deanery has the following parishes: St. Matthias Mulumba Parish in Misuku, St. Michaels Parish (covers Chitipa Central and North),
and St. Ignatius of Loyola Parish (Chitipa South).
Karonga Deanery has the following parishes: St. Anne’s Parish (Karonga South and Rumphi East), St. Mary’s Parish (Karonga Central),
St. Joseph the Worker Cathedral Parish (Karonga Central) and St. Steven’s Parish (Karonga North).